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Haegebarth
Product Name Pomalidomide-C3-acid Synonyms Pomalidomide-4'-C3-acid CAS Number 2225940-47-4 Related CAS Molecular Formula C17H17N3O6 Molecular Weight 359
Product Name Phthalimidinoglutarimide-C3-OH Synonyms Phthalimidinoglutarimide-4'-C3-OH CAS Number 2413731-71-0 Related CAS Molecular Formula C16H18N2O4 Molecular Weight 302
Fitzgibbons
DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:10mg HaegebarthSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
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